This month's episode is an encore presentation of an interview with Dr. Guy Caldwell from the University of Alabama. Dr. Caldwell explains how tools from molecular biology make it possible to use the famous C. Elegans roundworm to improve our understanding of neurodegenerative diseases like Parkinson's disease.

Dr. Caldwell will return to Brain Science next month to give us an update on his work.

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Links and References:

• Visit the Wormshack at the University of Alabama

• Meade, R. M., Fairlie, D. P., & Mason, J. M. (2019). Alpha-synuclein structure and Parkinson's disease - lessons and emerging principles. Molecular neurodegeneration, 14(1), 29. https://doi.org/10.1186/s13024-019-0329-1

• Gaeta, A. L., Caldwell, K. A., & Caldwell, G. A. (2019). Found in Translation: The Utility of C. elegans Alpha-Synuclein Models of Parkinson's Disease. Brain sciences, 9(4), 73. https://doi.org/10.3390/brainsci9040073

• See show notes for BSP 59 for additional references.

• Scroll up or click here for the free episode transcript.

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